• An incisional biopsy was undertaken Peri operative examinati

  2019-05-06

  

  An incisional biopsy was undertaken. Peri-operative examination of the lesion revealed an expansile tumor mass brownish in color with focal whitish areas (Fig. 3). The lesion could be delineated from the surrounding cortical bone, and surrounding soft tissues. Histopathologically the biopsy material

• Editorial opinion piece Many patients with advanced cancer w

  2019-05-06

  

  Editorial/opinion piece Many patients with advanced cancer will develop bone metastases and associated complications, including severe pain and debilitating skeletal-related events (SREs), which require radiotherapy, surgery or changes to antineoplastic regimens [1–3]. Fortunately, there are effect

• salubrinal Ad Mapu lleg a convertirse en un gran referente

  2019-05-06

  

  Ad Mapu llegó salubrinal convertirse en un gran referente que contribuyó al fortalecimiento de la conciencia de la situación mapuche, así lo explica Víctor Toledo al mencionar que es en este momento cuando aparece bosquejada la autodeterminación como propuesta del pueblo mapuche, y recuerda las pala

• Introduction Myelodysplastic Syndrome MDS is a heterogeneous

  2019-05-06

  

  Introduction Myelodysplastic Syndrome (MDS) is a heterogeneous clonal disorder characterized by ineffective hematopoeisis and propensity for transformation into Acute Myelogenous Leukemia (AML). The Revised International Prognostic Scoring System (R-IPSS) is an accepted model used to predict overal

• Based on the close relationship of

  2019-05-06

  

  Based on the close relationship of the canine wedge model to human ECGs, individuals with prominent J waves (ERS) or J/ST elevation (BS) are thought to have accentuated ventricular AP notch and the potential to lose their AP dome because of extrinsic factors such as vagal stimulation, sodium channel

• br Purpose br Methods Participating centers

  2019-05-06

  

  Purpose Methods Participating centers: Forty main ICSD centers in Japan from Hokkaido to Okinawa, which cover approximately 20% of all new ICSD patients in Japan, are participating in the present study. After obtaining written informed consent, all patients (over 20 years old) will be register

• br Conflict of interest br Introduction Bladder

  2019-05-06

  

  Conflict of interest Introduction Bladder cancer is one of the most common cancers in the world. It is estimated that around 74,000 new cases of Tyrosine Kinase Inhibitor Library cancer and 16,000 bladder cancer-related deaths will occur in the United States in 2015. It is prominent in men an

• br Introduction Once metastatic breast cancer cells are

  2019-05-06

  

  Introduction Once metastatic breast cancer sirtuin inhibitors are in the bone marrow, they hijack signals coming from the normal bone remodelling process and promote bone degradation [1]. Bone degradation is caused by osteoclasts, which have the unique property to dissolve bone mineral and degra

• Sin embargo m s all de las coincidencias

  2019-05-05

  

  Sin embargo, más allá de las coincidencias sobre qué hacer con y en el exilio, las significativas posiciones que se presentaron en sus páginas estuvieron lejos de mantener una posición unívoca. Como sugirió Gago, en Controversia pueden reconocerse al menos tres figuras: (1) el exilio como privilegio

• br The study by Jesse Berman and colleagues

  2019-05-05

  

  The study by Jesse Berman and colleagues published in is the first to systematically analyse the risk of hospital admissions and mortality associated with drought periods in the USA. As the authors state, this is an understudied topic, but of great concern in the USA and globally as climate chang

• The comparative consensus modelling approach used by Eaton a

  2019-05-05

  

  The comparative consensus modelling approach used by Eaton and colleagues is now used frequently to justify the implementation of particular HIV interventions. However, this approach produces meaningful results only if the comparison is based on valid models. Most comparative consensus studies (incl

• Pero en los a os noventa como

  2019-05-05

  

  Pero en los años noventa, como refere Brito, al inventariarse los resultados de la estrategia de desarrollo y de las reformas adelantadas en la década anterior, es decir ante una revisión “crítica” del “Consenso de Washington”, fue evidente que los costos en términos de inequidad y dualización socia

• La Proclama se alaba que las Fuerzas armadas

  2019-05-05

  

  La “Proclama” señalaba que las Fuerzas armadas asumían la conducción del Estado con el propósito de “terminar con el desgobierno, la corrupción y el flagelo subversivo.” En Guatemala, el “Comunicado Urgente al Pueblo” inmediatamente después del golpe del 23 de marzo de 1982 decía que: “El ejército

• br Authorship br Conflict of interest disclosure br Introduc

  2019-05-05

  

  Authorship Conflict of interest disclosure Introduction The Aurora kinases are serine/threonine protein kinases essential for regulation of normal crf hormone mitosis. Aurora kinases A (AAK) and B are overexpressed in hematologic malignancies, including acute myeloid leukemia (AML) and mye

• br With respect to the welfare of children and

  2019-05-05

  

  With respect to the welfare of children and mothers, the transition from the Millennium Development Goals (MDGs) to Sustainable Development Goals (SDGs) is sometimes perceived as risky. The relevant MDGs had a focus on interventions to address maternal and child health, while the focus of the SDGs

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