• Pulmonary fibroblasts can regulate the wound healing process

  2021-06-07

  

  Pulmonary fibroblasts can regulate the wound healing process by secreting and processing extracellular matrix (ECM), chemokines, and cytokines. However, persistent and atypical fibroblast proliferation can result in ECM accumulation and may trigger the onset or development of pulmonary fibrosis [[17

• Proteins that associate to PCNA

  2021-06-07

  

  Proteins that associate to PCNA are characterized by having conserved motifs as the PCNA-interacting protein (PIP) motif [29,30], its variant PIP-like motif [31,32] or the APIM motif (Alk B homologue 2 PCNA interacting motif [33,34]); for instance, p21 contains a PIP motif [30], and DNA polymerases

• Allele specific methylation has been observed in CpG

  2021-06-07

  

  Allele-specific methylation has been observed in CpG islands of imprinted genes.27, 32 In the present study, however, methylation of CpG1 was specific to ALL antibiotics and occurred in the leukemia cells of 28% of children with ALL, but it was not found in normal leukocytes from the same patients.

• Indeed some studies that examined the morphine response have

  2021-06-07

  

  Indeed, some studies that examined the morphine response have reported that the (C) allele of rs4818 was associated with a low dose administered compared to that given for individuals with the (G) allele (Rakvag et al., 2008). In a publication about Tunisian patients with cancer by Chatti et al. (2

• br Materials and methods br

  2021-06-07

  

  Materials and methods Results and discussion Conclusions Given that the activity of anti-plant virus compounds is related to host tobacco, virus, and compounds, we determined the effect of anti-CMV compound NNM on defense enzyme activity and chlorophyll index in tobacco, and we used RIB as

• An additional difference in ACC between H contortus and

  2021-06-07

  

  An additional difference in ACC-1 between H. contortus and C. elegans is the results from the oocyte expression experiments. Here we found that unlike Cel-ACC-1 that was reported to form a functional homomeric channel (Putrenko et al., 2005), Hco-ACC-1 does not. However, we have observed that in gen

• br Thy nephritis is one of

  2021-06-05

  

  Thy1.1 nephritis is one of the most commonly used models to study the course of immunoglobulin A and other mesangioproliferative nephropathies. To date, most of the studies have focused on mesangial and, to a lesser extent, endothelial cell recovery following capillary damage, whereas data concern

• EP EP and EP receptor

  2021-06-05

  

  EP1, EP3 and EP4 receptor expression on HMVEC-L was shown recently by flow cytometry [14]. However, only EP4 mRNA expression was previously described in these cells [49]. Our data obtained with RT-PCR showed EP4 mRNA and very low levels of EP1 mRNA, but no EP2 and EP3 mRNA expression was detectable

• br Acknowledgements br Introduction Endothelial cells consti

  2021-06-05

  

  Acknowledgements Introduction Endothelial cfse constitute a unique source of humoral factors that may regulate the functions of other cell types via paracrine or endocrine pathways [1]. Among the many molecules originated from the endothelium, nitric oxide (NO) plays versatile roles in mainta

• Recently cross talk between DDR and

  2021-06-05

  

  Recently, cross-talk between DDR2 and the insulin receptor and between Notch1 and DDR1 was proposed. Stimulation of cells with collagen I and insulin promotes Tyr740 as well as total tyrosine phosphorylation of DDR2 receptor to a greater extent than the phosphorylation stimulated by collagen I alone

• PRRSV is a single stranded

  2021-06-05

  

  PRRSV is a single-stranded, positive-sense enveloped RNA virus in the family Arteriviridae of the order Nidovirales (Meng et al., 1994, 1996). The PRRSV Anhydrotetracycline hydrochloride is approximately 15 kb in length and contains eleven known open reading frames (ORFs) (Snijder et al., 2013). The

• The imbalance that renders greater lipid uptake toxic

  2021-06-05

  

  The imbalance that renders greater lipid uptake toxic is unclear, but the comparison of our in vitro studies with those in mice illustrates the importance of TAG storage versus accumulation of less non-polar molecules. Protective effects of ACSL1 and PPARγ have been reported in other cell types. Par

• ELUXA HM EMSI is an ongoing

  2021-06-05

  

  ELUXA 1 (HM-EMSI-202) is an ongoing pivotal Phase II global clinical trial, designed to further investigate the efficacy and safety of Olmutinib in patients T790M-positive NSCLC with acquired resistance after first-line EGFR TKIs. Primary endpoint is ORR according to RECIST 1.1, while secondary endp

• br Materials and methods br Results and discussion br Summar

  2021-06-05

  

  Materials and methods Results and discussion Summary Acknowledgments We thank Muhammad Anwar for animal rearing and surgery. We also thank Michael M. Myers for editing. Finally, we thank David Hirschberg for his technical advice. Funding for this project was provided by the Einhorn Famil

• Crystallographic and NMR based analyses have revealed that

  2021-06-05

  

  Crystallographic and NMR-based analyses have revealed that RINGs and U-boxes have a common mode of interaction with E2s (Fig. 2A). The key structural elements are two loop-like regions, which, in the case of RINGs, coordinate Zn. The loops surround a shallow groove formed by the central α-helix. Tog

15883 records 647/1059 page Previous Next First page 上5页 646647648649650 下5页 Last page