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Following mutagenesis of the glucarpidase gene of Pseudomona
2021-04-26
Following mutagenesis of the glucarpidase gene of Pseudomonas sp. strain RS-16 [30], approximately 73% of the clones retained enzyme activity, as indicated by the clear zones and yellow precipitate surrounding their colonies. However, there were very few that had ‘halos’ around colonies that were da
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Wu et al explored the anti inflammatory mechanisms
2021-04-26
Wu et al. explored the anti-inflammatory mechanisms by which osthole 35 acted on HepG2 cells cultured in a differentiated medium from cultured 3T3-L1 preadipocyte cells. HepG2 cells, a human liver cell line, were treated with various concentrations of osthole 35 in differentiated media from cultured
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Furthermore many intermediate plants did not show additive c
2021-04-26
Furthermore, many intermediate plants did not show additive combinations of parental allozymes, which would be expected in F1 hybrids. The absence of some characteristic parental bands suggests that sexual reproduction has occurred among the hybrid plants. Genetic variations within and among the int
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Assessment of DNA damage by comet assay and
2021-04-26
Assessment of DNA damage by comet assay and ChEs activity has been widely used as a biomarker of genotoxicity and exposure to pesticide respectively, to measure the risk related to pesticides in the exposed population [15]. Very few studies have explored the association between DNA damage and worker
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It was reported that IVM modulates
2021-04-26
It was reported that IVM modulates various ion channels, such as type-A GABACls, α7 acetylcholine-gated cation channels, P2X4 ATP-gated cation channels, and glycine-gated chloride Axitinib in vertebrates (Adelsberger et al., 2000, Khakh et al., 1999, Krause et al., 1998, Krůšek and Zemková, 1994, S
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The N B method has the overall advantage that
2021-04-26
The N&B method has the overall advantage that it is not restricted to certain dyes specific for energy transfer [55], and is also able to detect higher order receptor amc 7 on the focal point in living cells. Conclusion The N&B method has shown to be a powerful tool to locate and quantify the a
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More importantly Santagata et al have suggested a
2021-04-26
More importantly, Santagata et al. have suggested a new breast cancer subtyping method according to ER, androgen receptor (AR), and VDR with a higher prognostic value than the ordinarily used method based on ER, progesterone receptor (PR) and Her2 (Santagata et al., 2014). This implies that such com
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To our knowledge immunohistochemical analysis for proGRP was
2021-04-26
To our knowledge, immunohistochemical analysis for proGRP was done in 5 cases [9], [10], [17], [18]. Takagi-Takahashi et al. reported that the tumor chloroquine phosphate mg were positive for proGRP in one case [9]. Yamaguchi et al. also showed that tumor cells in two patients of ES/PNET with eleva
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Although our knowledge of the biochemical and biological fun
2021-04-25
Although our knowledge of the biochemical and biological functions of E3 ubiquitin ligases has increased in B-cell malignancies, a deeper characterization of cell-context dependent substrate regulation and biological relevance is needed. The recent approval of a general proteasome inhibitor, VELCADE
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FOX proteins constitute a large class of transcription
2021-04-25
FOX proteins constitute a large class of transcription factors with multiple functions, from development and organogenesis to regulation of metabolic and immune functions. The Fox transcription factor is characterized by a 100-amino-acid wing helix or forkhead DNA-binding domain. In addition, the FO
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CellProfiler and OpenComet are two open source
2021-04-25
CellProfiler and OpenComet are two open source software available in internet to analyse silver stained comet assay images. With CellProfiler [19], Gonzalez et al. [18] modified the pipeline provided in the website by adding a background subtraction module and two filtering modules to quantify DNA d
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Defensins are one major class of antimicrobial cationic pept
2021-04-25
Defensins are one major class of antimicrobial, cationic peptides that are released from Erastin and imbedded in the mucus layer on mucosal surfaces [45]. They can be categorized into two major families; α- and β-defensins. In humans there are two α-defensin members, defensin 5 (HD5) and defensin 6
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In addition to the blockade of airway smooth muscle contract
2021-04-25
In addition to the blockade of airway smooth muscle contractions, CysLT1 receptor antagonists also exerted a potent anti-inflammatory effect at this level. The oral administration of MEN91507, Pranlukast, Montelukast, and Zafirlukast also produced a long-lasting inhibition of leukotriene D4-induced
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Besides the enhanced expression of
2021-04-25
Besides the enhanced expression of costimulatory and adhesion proteins, also the expression of the CD83 surface molecule is strongly enhanced during DC maturation (Banchereau and Steinman 1998; Banchereau et al. 2000). In fact, CD83 is a major cell surface marker for fully mature DC, as it can not b
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Table gives the list of components which will
2021-04-25
Table 1 gives the list of components which will be modeled. Transient Voltage Suppressor (TVS) as well as passive elements will be also modeled. For each component, we will choose the EMC (emission and immunity) and transient immunity measurement method adapted to extract the component model. A com
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